The medication/dose was equivalent to giving a human 500 mg of ibuprofen every eight hours. In the study, mice were randomly assigned to two groups: One group was given NSAID injections during rest periods every day for three days following surgery (akin to taking medication at night) the other received the same NSAID dose for the same period but it was administered at a time of day when the mice would normally be active (akin to taking medication during the day). This preliminary finding comes from a study that compared the effects of NSAID timing on pain and post-operative healing in 16 mice who had tibia (shinbone) fracture surgery. While reaching for these drugs whenever pain strikes might seem like the obvious way to go (unless your doctor has instructed you to avoid them or take them prophylactically), there might be another factor to consider: the time of day when you take them.Īccording to a new study, published in the journal Scientific Reports, using NSAIDs during the daytime might be preferable to taking them at night (such as before bed). Many arthritis patients use non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen, to ease pain, as do many people who are recovering from various types of surgery.
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